CMTM6 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CMTM6 full-length ORF (NP_060271.1, 1 a.a. - 183 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
MENGAVYSPTTEEDPGPARGPRSGLAAYFFMGRLPLLRRVLKGLQLLLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILIVYCTPFYERVDTTKVKSSDFYITLGTGCVFLLASIIFVSTHDRTSAEIAAIVFGFIASFMFLLDFITMLYEKRQESQLRKPENTTRAEALTEPLNA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.8
Interspecies Antigen Sequence
Mouse (83); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CMTM6
Entrez GeneID
54918GeneBank Accession#
NM_017801.2Protein Accession#
NP_060271.1Gene Name
CMTM6
Gene Alias
CKLFSF6, FLJ20396, PRO2219
Gene Description
CKLF-like MARVEL transmembrane domain containing 6
Omim ID
607889Gene Ontology
HyperlinkGene Summary
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq
Other Designations
chemokine-like factor super family 6|chemokine-like factor superfamily 6
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Interactome
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Publication Reference
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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Patricia Ho, Johannes C Melms, Meri Rogava, Chris J Frangieh, Joanna Poźniak, Shivem B Shah, Zachary Walsh, Oleksandr Kyrysyuk, Amit Dipak Amin, Lindsay Caprio, Benjamin T Fullerton, Rajesh Kumar Soni, Casey R Ager, Jana Biermann, Yiping Wang, Mohsen Khosravi-Maharlooei, Giorgia Zanetti, Michael Mu, Hijab Fatima, Emily K Moore, Neil Vasan, Samuel F Bakhoum, Steven L Reiner, Chantale Bernatchez, Megan Sykes, Emily M Mace, Kai W Wucherpfennig, Dirk Schadendorf, Oliver Bechter, Parin Shah, Gary K S
Cancer Cell 2023 Jul; 41(7):1207.
Application:Sub, N/A, Recombinant proteins.
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The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
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