PXK rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PXK peptide using ARM Technology.
Immunogen
A synthetic peptide of human PXK is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PXK peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PXK
Entrez GeneID
54899GeneBank Accession#
PXKGene Name
PXK
Gene Alias
FLJ20335, MONaKA
Gene Description
PX domain containing serine/threonine kinase
Omim ID
611450Gene Ontology
HyperlinkGene Summary
PXK binds to the Na,K-ATPase beta-1 (ATP1B1; MIM 182330) and beta-3 (ATP1B3; MIM 601867) subunits and modulates both Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005 [PubMed 16135750]).[supplied by OMIM
Other Designations
PX ser/thr kinase v2|PX serine/threonine kinase|modulator of Na,K-ATPase long form
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Interactome
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Disease
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