APTX purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human APTX protein.
Immunogen
APTX (NP_778242.1, 1 a.a. ~ 254 a.a) full-length human protein.
Sequence
MVNELYPYIVEFEEEAKNPGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (79)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of APTX expression in transfected 293T cell line (H00054840-T01) by APTX MaxPab polyclonal antibody.
Lane 1: APTX transfected lysate(27.94 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to APTX on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — APTX
Entrez GeneID
54840GeneBank Accession#
NM_175072.1Protein Accession#
NP_778242.1Gene Name
APTX
Gene Alias
AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, FLJ20157, MGC1072
Gene Description
aprataxin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000021188|ataxia 1, early onset with hypoalbuminemia
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Interactome
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Disease
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