TRPM7 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TRPM7 partial ORF ( NP_060142.2, 777 a.a. - 855 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.43
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TRPM7
Entrez GeneID
54822GeneBank Accession#
NM_017672Protein Accession#
NP_060142.2Gene Name
TRPM7
Gene Alias
CHAK, CHAK1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK
Gene Description
transient receptor potential cation channel, subfamily M, member 7
Gene Ontology
HyperlinkGene Summary
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM
Other Designations
LTRPC ion channel family member 7
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Interactome
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Disease
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