This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations:
LIS1-interacting protein NUDE1, rat homolog,OTTHUMP00000160329,OTTHUMP00000160330,nuclear distribution gene E homolog 1