FBLIM1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human FBLIM1 full-length ORF (BAB55115.1, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGDICAFYHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
57.2
Interspecies Antigen Sequence
Mouse (59); Rat (74)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FBLIM1
Entrez GeneID
54751GeneBank Accession#
AK027444.1Protein Accession#
BAB55115.1Gene Name
FBLIM1
Gene Alias
CAL, DKFZp434G171, FBLP-1, FBLP1, RP11-169K16.5
Gene Description
filamin binding LIM protein 1
Omim ID
607747Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CSX-associated LIM|MIG2-interacting protein|OTTHUMP00000003118|OTTHUMP00000003119|OTTHUMP00000003120|filamin-binding LIM protein-1|migfilin|mitogen-inducible 2 interacting protein
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Interactome
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