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Last updated: 2016/10/23

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FBLIM1 rabbit monoclonal antibody

  • Catalog # : H00054751-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human FBLIM1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human FBLIM1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human FBLIM1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Gene Name:
  • FBLIM1
  • Gene Alias:
  • CAL,DKFZp434G171,FBLP-1,FBLP1,RP11-169K16.5
  • Gene Description:
  • filamin binding LIM protein 1
  • Gene Summary:
  • This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • CSX-associated LIM,MIG2-interacting protein,OTTHUMP00000003118,OTTHUMP00000003119,OTTHUMP00000003120,filamin-binding LIM protein-1,migfilin,mitogen-inducible 2 interacting protein
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