FEV polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant FEV.
Immunogen
FEV (NP_059991, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag.
Sequence
PSWGPLSPAVQKGSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — FEV
Entrez GeneID
54738GeneBank Accession#
NM_017521Protein Accession#
NP_059991Gene Name
FEV
Gene Alias
HSRNAFEV, PET-1
Gene Description
FEV (ETS oncogene family)
Omim ID
607150Gene Ontology
HyperlinkGene Summary
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq
Other Designations
FEV (fifth Ewing variant)|OTTHUMP00000164098
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Interactome
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Disease
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Publication Reference
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Tumor Suppressor Role and Clinical Significance of the FEV Gene in Prostate Cancer.
Yu-Xiang Liang, Ying-Ke Liang, Zhi-Hao Zou, Yang-Jia Zhuo, Jian-Heng Ye, Xue-Jin Zhu, Zhou-Da Cai, Zhuo-Yuan Lin, Ru-Jun Mo, Shu-Lin Wu, Yan-Qiong Zhang, Wei-De Zhong.
Disease Markers 2022 May; 2022:8724035.
Application：WB, Human, 22RV1, BPH-1, DU-145, LNCaP, PC-3 cells.
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Tumor Suppressor Role and Clinical Significance of the FEV Gene in Prostate Cancer.
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