MARCH5 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MARCH5 full-length ORF ( NP_060294.1, 1 a.a. - 278 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
57.6
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MARCH5
Entrez GeneID
54708GeneBank Accession#
NM_017824.4Protein Accession#
NP_060294.1Gene Name
MARCH5
Gene Alias
FLJ20445, MARCH-V, MITOL, RNF153
Gene Description
membrane-associated ring finger (C3HC4) 5
Omim ID
610637Gene Ontology
HyperlinkGene Summary
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM
Other Designations
OTTHUMP00000020096|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153
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