MARCH5 monoclonal antibody (M06), clone 3C3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MARCH5.
Immunogen
MARCH5 (NP_060294.1, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MARCH5 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — MARCH5
Entrez GeneID
54708GeneBank Accession#
NM_017824.4Protein Accession#
NP_060294.1Gene Name
MARCH5
Gene Alias
FLJ20445, MARCH-V, MITOL, RNF153
Gene Description
membrane-associated ring finger (C3HC4) 5
Omim ID
610637Gene Ontology
HyperlinkGene Summary
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM
Other Designations
OTTHUMP00000020096|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153
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