MARCH5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MARCH5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MARCH5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MARCH5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MARCH5
Entrez GeneID
54708GeneBank Accession#
MARCH5Gene Name
MARCH5
Gene Alias
FLJ20445, MARCH-V, MITOL, RNF153
Gene Description
membrane-associated ring finger (C3HC4) 5
Omim ID
610637Gene Ontology
HyperlinkGene Summary
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM
Other Designations
OTTHUMP00000020096|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153
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Interactome
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