P4HTM rabbit monoclonal antibody
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Specifications
Product Description
Rabbit monoclonal antibody raised against a human P4HTM peptide using ARM Technology.
Immunogen
A synthetic peptide of human P4HTM is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human P4HTM peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — P4HTM
Entrez GeneID
54681GeneBank Accession#
P4HTMGene Name
P4HTM
Gene Alias
EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4
Gene Description
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000082685|P4H with transmembrane domain|Prolyl hydroxlase domain-containing 4|hypoxia inducible factor prolyl 4 hydroxylase|hypoxia-inducible factor prolyl 4-hydroxylase|proline 4-hydroxylase
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Interactomes
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Toll Free : +1-877-853-6098 - +1-909-992-3401
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