FBXL19 monoclonal antibody (M03), clone 3C5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FBXL19.
Immunogen
FBXL19 (NP_061958.1, 365 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.62 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FBXL19 is 3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to FBXL19 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — FBXL19
Entrez GeneID
54620GeneBank Accession#
NM_019085Protein Accession#
NP_061958.1Gene Name
FBXL19
Gene Alias
DKFZp434K0410, Fbl19, JHDM1C, MGC50505
Gene Description
F-box and leucine-rich repeat protein 19
Omim ID
609085Gene Ontology
HyperlinkGene Summary
Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM
Other Designations
jumonji C domain-containing histone demethylase 1C
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Interactome
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Disease
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