GNB1L (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GNB1L partial ORF ( NP_443730, 98 a.a. - 207 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AEGRSAVVDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDEVQILEMPSKTSVCALKPKADAKLGMPMCLRLWQADCSSRPLLLAGYEDGSVVLWDVSEQKVCSRIACH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (81); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GNB1L
Entrez GeneID
54584GeneBank Accession#
NM_053004Protein Accession#
NP_443730Gene Name
GNB1L
Gene Alias
DGCRK3, FKSG1, GY2, KIAA1645, WDR14, WDVCF
Gene Description
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Omim ID
610778Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq
Other Designations
G-protein beta subunit-like protein|guanine nucleotide binding protein beta-subunit-like polypeptide
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Interactome
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Disease
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