XRN1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human XRN1 protein.
Immunogen
XRN1 (AAH48104.1, 1 a.a. ~ 459 a.a) full-length human protein.
Sequence
MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMAKLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSEYVFANAFILK
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of XRN1 expression in transfected 293T cell line (H00054464-T02) by XRN1 MaxPab polyclonal antibody.
Lane 1: XRN1 transfected lysate(53.80 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — XRN1
Entrez GeneID
54464GeneBank Accession#
BC048104.1Protein Accession#
AAH48104.1Gene Name
XRN1
Gene Alias
DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1
Gene Description
5'-3' exoribonuclease 1
Omim ID
607994Gene Ontology
HyperlinkGene Summary
SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM
Other Designations
strand-exchange protein 1
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Interactome
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Pathway
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