FBXW5 mouse monoclonal antibody (hybridoma)
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant FBXW5.
Immunogen
FBXW5 (AAH00850.1, 1 a.a. ~ 159 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (93)
Quality Control Testing
Antibody reactivity and specificity confirmed by ELISA and Western Blot.
Deliverables
Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
Note
Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
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Applications
Western Blot (Transfected lysate)
Western Blot (Recombinant protein)
ELISA
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Gene Info — FBXW5
Entrez GeneID
54461GeneBank Accession#
BC000850.1Protein Accession#
AAH00850.1Gene Name
FBXW5
Gene Alias
DKFZp434B205, Fbw5, MGC20962, RP11-229P13.10
Gene Description
F-box and WD repeat domain containing 5
Omim ID
609072Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq
Other Designations
F-box and WD-40 domain protein 5|OTTHUMP00000022659|WD repeat-containing F-box protein FBW5
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Interactomes
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