HAO1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HAO1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HAO1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HAO1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HAO1
Entrez GeneID
54363GeneBank Accession#
HAO1Gene Name
HAO1
Gene Alias
GOX, GOX1, HAOX1, MGC142225, MGC142227
Gene Description
hydroxyacid oxidase (glycolate oxidase) 1
Omim ID
605023Gene Ontology
HyperlinkGene Summary
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq
Other Designations
(S)-2-hydroxy-acid oxidase|OTTHUMP00000030231|glycolate oxidase|hydroxyacid oxidase 1
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