SOX18 monoclonal antibody (M05), clone 1C4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SOX18.
Immunogen
SOX18 (NP_060889, 63 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SOX18 monoclonal antibody (M05), clone 1C4. Western Blot analysis of SOX18 expression in human kidney.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SOX18 is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SOX18 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SOX18
Entrez GeneID
54345GeneBank Accession#
NM_018419Protein Accession#
NP_060889Gene Name
SOX18
Gene Alias
HLTS
Gene Description
SRY (sex determining region Y)-box 18
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq
Other Designations
OTTHUMP00000031624|SRY-box 18|Transcription factor SOX-18
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Interactome
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Disease
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