TREM1 DNAxPab
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of TREM1 expression in transfected 293T cell line by TREM1 DNAxPab polyclonal antibody.
Lane 1: TREM1 transfected lysate(41.47 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human TREM1 DNA using DNAx™ Immune technology.
Technology
Immunogen
TREM1 (NP_061113.1, 21 a.a. ~ 205 a.a) partial-length human DNA
Sequence
ATKLTEEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRMVNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSGTPGSNENSTQNVYKIPPTTTKALCPLYTSPRTVTQAPPKSTADVSTPDSEINLTNVTDIIRVPVFN
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TREM1 expression in transfected 293T cell line by TREM1 DNAxPab polyclonal antibody.
Lane 1: TREM1 transfected lysate(41.47 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — TREM1
Entrez GeneID
54210GeneBank Accession#
NM_018643.2Protein Accession#
NP_061113.1Gene Name
TREM1
Gene Alias
TREM-1
Gene Description
triggering receptor expressed on myeloid cells 1
Omim ID
605085Gene Ontology
HyperlinkGene Summary
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
Other Designations
OTTHUMP00000016370|triggering-receptor TREM1
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Interactome
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Disease
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