TREM1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TREM1 full-length
Host
Human
Theoretical MW (kDa)
25.85
Interspecies Antigen Sequence
Mouse (45); Rat (46)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TREM1 antibody (H00054210-B01) by Western Blots.
SDS-PAGE Gel
TREM1 transfected lysate.
Western Blot
Lane 1: TREM1 transfected lysate ( 25.85 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TREM1
Entrez GeneID
54210GeneBank Accession#
NM_018643Protein Accession#
NP_061113Gene Name
TREM1
Gene Alias
TREM-1
Gene Description
triggering receptor expressed on myeloid cells 1
Omim ID
605085Gene Ontology
HyperlinkGene Summary
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
Other Designations
OTTHUMP00000016370|triggering-receptor TREM1
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