TREM1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TREM1 full-length ORF ( AAH17773.1, 21 a.a. - 234 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ATKLTEEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRMVNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSGTPGSNENSTQNVYKIPPTTTKALCPLYTSPRTVTQAPPKSTADVSTPDSEINLTNVTDIIRVPVFNIVILLAGGFLSKSLVFSVLFAVTLRSFVP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.28
Interspecies Antigen Sequence
Mouse (45); Rat (46)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TREM1
Entrez GeneID
54210GeneBank Accession#
BC017773Protein Accession#
AAH17773.1Gene Name
TREM1
Gene Alias
TREM-1
Gene Description
triggering receptor expressed on myeloid cells 1
Omim ID
605085Gene Ontology
HyperlinkGene Summary
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
Other Designations
OTTHUMP00000016370|triggering-receptor TREM1
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Interactome
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Disease
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Publication Reference
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Development of Immunosensors for Direct Detection of Three Wound Infection Biomarkers at Point of Care using Electrochemical Impedance Spectroscopy.
Ciani I, Schulze H, Corrigan DK, Henihan G, Giraud G, Terry JG, Walton AJ, Pethig R, Ghazal P, Crain J, Campbell CJ, Bachmann TT, Mount AR.
Biosensors & Bioelectronics 2012 Jan; 31(1):413.
Application：ELISA, Recombinant protein.
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Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils.
Li J, Birkenheuer AJ, Marr HS, Levy MG, Yoder JA, Nordone SK.
Developmental and Comparative Immunology 2011 Aug; 35(8):872.
Application：WB, E. coli, BL21 Star cells.
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Development of Immunosensors for Direct Detection of Three Wound Infection Biomarkers at Point of Care using Electrochemical Impedance Spectroscopy.
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