TREM2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TREM2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TREM2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TREM2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TREM2
Entrez GeneID
54209GeneBank Accession#
TREM2Gene Name
TREM2
Gene Alias
TREM-2, Trem2a, Trem2b, Trem2c
Gene Description
triggering receptor expressed on myeloid cells 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). [provided by RefSeq
Other Designations
OTTHUMP00000016368|OTTHUMP00000039771|triggering receptor expressed on monocytes 2|triggering receptor expressed on myeloid cells 2a
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Interactome
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Disease
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