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TREM2 rabbit monoclonal antibody

  • Catalog # : H00054209-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TREM2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TREM2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TREM2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • TREM2
  • Gene Name:
  • TREM2
  • Gene Alias:
  • TREM-2,Trem2a,Trem2b,Trem2c
  • Gene Description:
  • triggering receptor expressed on myeloid cells 2
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016368,OTTHUMP00000039771,triggering receptor expressed on monocytes 2,triggering receptor expressed on myeloid cells 2a
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