KCNK10 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KCNK10 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KCNK10 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KCNK10 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KCNK10
Entrez GeneID
54207GeneBank Accession#
KCNK10Gene Name
KCNK10
Gene Alias
FLJ43399, K2p10.1, TREK-2, TREK2
Gene Description
potassium channel, subfamily K, member 10
Omim ID
605873Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
2P domain potassium channel TREK2|TWIK-related K+ channel 2|outward rectifying potassium channel protein TREK-2|potassium channel TREK-2
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Interactome
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