POLE3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POLE3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human POLE3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POLE3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POLE3
Entrez GeneID
54107GeneBank Accession#
POLE3Gene Name
POLE3
Gene Alias
CHARAC17, CHRAC17, YBL1, p17
Gene Description
polymerase (DNA directed), epsilon 3 (p17 subunit)
Omim ID
607267Gene Ontology
HyperlinkGene Summary
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM
Other Designations
DNA polymerase epsilon p17 subunit|DNA polymerase epsilon subunit 3|OTTHUMP00000021954|OTTHUMP00000021955|arsenic transactivated protein|chromatin accessibility complex 17|histone fold protein CHRAC17
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Interactome
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Pathway
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