Western blot analysis of CSNK1G1 over-expressed 293 cell line, cotransfected with CSNK1G1 Validated Chimera RNAi ( Cat # H00053944-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CSNK1G1 monoclonal antibody (M03), clone 3F10 (Cat # H00053944-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Casein kinase I is the most abundant serine/threonine kinase in eukaryotic cell extracts. Multiple isoforms of the enzyme exist. The gamma-1 isoform is involved in growth and morphogenesis of eukaryotic cells.[supplied by OMIM