MYO3A monoclonal antibody (M08), clone 8H2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MYO3A.
Immunogen
MYO3A (NP_059129, 1400 a.a. ~ 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKIL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94)
Isotype
IgG2b
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MYO3A monoclonal antibody (M08), clone 8H2 Western Blot analysis of MYO3A expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — MYO3A
Entrez GeneID
53904GeneBank Accession#
NM_017433Protein Accession#
NP_059129Gene Name
MYO3A
Gene Alias
DFNB30
Gene Description
myosin IIIA
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq
Other Designations
OTTHUMP00000019339
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Interactome
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Disease
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