S1PR5 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human S1PR5 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — S1PR5
Entrez GeneID
53637GeneBank Accession#
NM_030760.3Protein Accession#
NP_110387.1Gene Name
S1PR5
Gene Alias
EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Gene Description
sphingosine-1-phosphate receptor 5
Omim ID
605146Gene Ontology
HyperlinkGene Summary
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM
Other Designations
endothelial differentiation, sphingolipid G-protein-coupled receptor, 8|sphingosine 1-phosphate receptor 5|sphingosine 1-phosphate receptor Edg-8
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Interactome
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Disease
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