EDG8 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human EDG8 full-length ORF ( NP_110387.1, 1 a.a. - 398 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
68.2
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — S1PR5
Entrez GeneID
53637GeneBank Accession#
NM_030760.3Protein Accession#
NP_110387.1Gene Name
S1PR5
Gene Alias
EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Gene Description
sphingosine-1-phosphate receptor 5
Omim ID
605146Gene Ontology
HyperlinkGene Summary
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM
Other Designations
endothelial differentiation, sphingolipid G-protein-coupled receptor, 8|sphingosine 1-phosphate receptor 5|sphingosine 1-phosphate receptor Edg-8
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Interactome
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Pathway
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Disease
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