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Last updated: 2016/12/4

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S1PR5 rabbit monoclonal antibody

  • Catalog # : H00053637-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human S1PR5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human S1PR5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human S1PR5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • S1PR5
  • Gene Name:
  • S1PR5
  • Gene Alias:
  • EDG8,Edg-8,S1P5,SPPR-1,SPPR-2
  • Gene Description:
  • sphingosine-1-phosphate receptor 5
  • Gene Summary:
  • The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM
  • Other Designations:
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8,sphingosine 1-phosphate receptor 5,sphingosine 1-phosphate receptor Edg-8
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