PRKAG3 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PRKAG3 expression in transfected 293T cell line (H00053632-T01) by PRKAG3 MaxPab polyclonal antibody.
Lane 1: PRKAG3 transfected lysate(54.30 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PRKAG3 protein.
Immunogen
PRKAG3 (NP_059127.2, 1 a.a. ~ 489 a.a) full-length human protein.
Sequence
MEPGLEHALRRTPSWSSLGGSEHQEMSFLEQENSSSWPSPAVTSSSERIRGKRRAKALRWTRQKSVEEGEPPGQGEGPRSRPAAESTGLEATFPKTTPLAQADPAGVGTPPTGWDCLPSDCTASAAGSSTDDVELATEFPATEAWECELEGLLEERPALCLSPQAPFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPLVSISPNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PRKAG3 expression in transfected 293T cell line (H00053632-T01) by PRKAG3 MaxPab polyclonal antibody.
Lane 1: PRKAG3 transfected lysate(54.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PRKAG3
Entrez GeneID
53632GeneBank Accession#
NM_017431Protein Accession#
NP_059127.2Gene Name
PRKAG3
Gene Alias
AMPKG3
Gene Description
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Omim ID
604976Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq
Other Designations
5'-AMP-activated protein kinase, gamma-3 subunit|AMP-activated protein kinase, non-catalytic gamma-3 subunit|AMPK gamma-3 chain|OTTHUMP00000164095
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Interactome
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Pathway
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Disease
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