ADAM22 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ADAM22 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ADAM22 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ADAM22 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ADAM22
Entrez GeneID
53616GeneBank Accession#
ADAM22Gene Name
ADAM22
Gene Alias
MDC2, MGC149832
Gene Description
ADAM metallopeptidase domain 22
Omim ID
603709Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. Alternative splicing results in several transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000174585|OTTHUMP00000174587|OTTHUMP00000174589|a disintegrin and metalloproteinase domain 22|metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
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Interactome
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Disease
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