CLIC5 monoclonal antibody (M03), clone 1E6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLIC5.
Immunogen
CLIC5 (NP_058625.2, 91 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CLIC5 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CLIC5 on HeLa cell . [antibody concentration 20 ug/ml] -
Gene Info — CLIC5
Entrez GeneID
53405GeneBank Accession#
NM_016929Protein Accession#
NP_058625.2Gene Name
CLIC5
Gene Alias
CLIC5B, FLJ90663, MST130, MSTP130, dJ447E21.4
Gene Description
chloride intracellular channel 5
Omim ID
607293Gene Ontology
HyperlinkGene Summary
Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 specifically associates with the cytoskeleton of placenta microvilli.[supplied by OMIM
Other Designations
OTTHUMP00000016538|chloride intracellular channel 5A
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Interactome
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Disease
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Publication Reference
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CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity.
Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ.
American Journal of Physiology. Renal Physiology 2010 Jun; 298(6):F1492.
Application:IF, IP, WB-Ti, Mouse, Human renal glomeruli, Mouse kidney cortex.
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CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity.
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