PANK1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PANK1 full-length
Host
Human
Theoretical MW (kDa)
41.14
Interspecies Antigen Sequence
Mouse (96); Rat (98)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PANK1 antibody (H00053354-B01) by Western Blots.
SDS-PAGE Gel
PANK1 transfected lysate.
Western Blot
Lane 1: PANK1 transfected lysate ( 41.14 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PANK1
Entrez GeneID
53354GeneBank Accession#
NM_148978.1Protein Accession#
NP_683879.1Gene Name
PANK1
Gene Alias
MGC24596, PANK, PANK1a, PANK1b
Gene Description
pantothenate kinase 1
Omim ID
606160Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000020071|OTTHUMP00000020072|pantothenic acid kinase
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Pathway
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Disease
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