BCL11A 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
BCL11A transfected lysate.
Western Blot
Lane 1: BCL11A transfected lysate ( 26.84 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BCL11A full-length
Host
Human
Theoretical MW (kDa)
26.84
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BCL11A antibody (H00053335-B01) by Western Blots.
SDS-PAGE Gel
BCL11A transfected lysate.
Western Blot
Lane 1: BCL11A transfected lysate ( 26.84 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BCL11A
Entrez GeneID
53335GeneBank Accession#
NM_138559.1Protein Accession#
NP_612569.1Gene Name
BCL11A
Gene Alias
BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Gene Description
B-cell CLL/lymphoma 11A (zinc finger protein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell CLL/lymphoma 11A|C2H2-type zinc finger protein|ecotropic viral integration site 9 homolog
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Interactome
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Disease
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