BCL11A (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of BCL11A transfected lysate using rabbit polyclonal anti-BCL11A and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BCL11A.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of BCL11A transfected lysate using rabbit polyclonal anti-BCL11A and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-BCL11A.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-BCL11A (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-BCL11A (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — BCL11A
Entrez GeneID
53335Gene Name
BCL11A
Gene Alias
BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Gene Description
B-cell CLL/lymphoma 11A (zinc finger protein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell CLL/lymphoma 11A|C2H2-type zinc finger protein|ecotropic viral integration site 9 homolog
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Interactome
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Disease
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