BCL11A MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of BCL11A expression in transfected 293T cell line (H00053335-T01) by BCL11A MaxPab polyclonal antibody.
Lane 1: BCL11A transfected lysate(26.90 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of BCL11A transfected lysate using anti-BCL11A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with BCL11A purified MaxPab mouse polyclonal antibody (B01P) (H00053335-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human BCL11A protein.
Immunogen
BCL11A (NP_612569.1, 1 a.a. ~ 243 a.a) full-length human protein.
Sequence
MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKAVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQGICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVLHTPPFGVVPRELKMCGSFRMEAREPLSSEKI
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BCL11A expression in transfected 293T cell line (H00053335-T01) by BCL11A MaxPab polyclonal antibody.
Lane 1: BCL11A transfected lysate(26.90 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of BCL11A transfected lysate using anti-BCL11A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with BCL11A purified MaxPab mouse polyclonal antibody (B01P) (H00053335-B01P). -
Gene Info — BCL11A
Entrez GeneID
53335GeneBank Accession#
NM_138559.1Protein Accession#
NP_612569.1Gene Name
BCL11A
Gene Alias
BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Gene Description
B-cell CLL/lymphoma 11A (zinc finger protein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell CLL/lymphoma 11A|C2H2-type zinc finger protein|ecotropic viral integration site 9 homolog
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Interactome
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Disease
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