CALML5 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CALML5 partial ORF ( NP_059118, 47 a.a. - 146 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AQLRKLISEVDSDGDGEISFQEFLTAARKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (51); Rat (51)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CALML5
Entrez GeneID
51806GeneBank Accession#
NM_017422Protein Accession#
NP_059118Gene Name
CALML5
Gene Alias
CLSP
Gene Description
calmodulin-like 5
Omim ID
605183Gene Ontology
HyperlinkGene Summary
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq
Other Designations
OTTHUMP00000019005|calmodulin-like skin protein
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Interactome
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Pathway
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