CD244 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
CD244 MaxPab rabbit polyclonal antibody. Western Blot analysis of CD244 expression in mouse liver.
Western Blot (Transfected lysate)
Western Blot analysis of CD244 expression in transfected 293T cell line (H00051744-T02) by CD244 MaxPab polyclonal antibody.
Lane 1: CD244 transfected lysate(41.10 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CD244 protein.
Immunogen
CD244 (NP_057466.1, 1 a.a. ~ 365 a.a) full-length human protein.
Sequence
MLGQVVTLILLLLLKVYQGKGCQGSADHVVSISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNLSLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVALSCLVSRDGNVSYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTSQEPAYTLYSLIQPSRKSGSRKRNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (48); Rat (43)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CD244 MaxPab rabbit polyclonal antibody. Western Blot analysis of CD244 expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of CD244 expression in transfected 293T cell line (H00051744-T02) by CD244 MaxPab polyclonal antibody.
Lane 1: CD244 transfected lysate(41.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CD244
Entrez GeneID
51744GeneBank Accession#
NM_016382.2Protein Accession#
NP_057466.1Gene Name
CD244
Gene Alias
2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Gene Description
CD244 molecule, natural killer cell receptor 2B4
Omim ID
605554Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM
Other Designations
CD244 natural killer cell receptor 2B4|NK cell activation inducing ligand NAIL|OTTHUMP00000027884|natural killer cell receptor 2B4
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Interactome
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Pathway
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Disease
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