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WWOX Pre-design Chimera RNAi

  • Catalog # : H00051741-R05
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens WW domain containing oxidoreductase (WWOX), transcript variant 6, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_130791
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • WWOX
  • Gene Alias:
  • D16S432E,FOR,FRA16D,HHCMA56,PRO0128,SDR41C1,WOX1
  • Gene Description:
  • WW domain containing oxidoreductase
  • Gene Summary:
  • WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq
  • Other Designations:
  • WW domain-containing oxidoreductase,WW domain-containing protein WWOX,fragile 16D oxido reductase,fragile site FRA16D oxidoreductase,putative oxidoreductase,short chain dehydrogenase/reductase family 41C, member 1
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