RAPGEF6 monoclonal antibody (M01), clone 2C5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RAPGEF6.
Immunogen
RAPGEF6 (NP_057424, 1012 a.a. ~ 1110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LFPVVKKDMTFLHEGNDSKVDGLVNFEKLRMISKEIRQVVRMTSANMDPAMMFRQRSLSQGSTNSNMLDVQGGAHKKRARRSSLLNAKKLYEDAQMARK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RAPGEF6 monoclonal antibody (M01), clone 2C5 Western Blot analysis of RAPGEF6 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to RAPGEF6 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to RAPGEF6 on HeLa cell. [antibody concentration 40 ug/ml] -
Gene Info — RAPGEF6
Entrez GeneID
51735GeneBank Accession#
NM_016340Protein Accession#
NP_057424Gene Name
RAPGEF6
Gene Alias
DKFZp667N084, DKFZp686I15116, KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2
Gene Description
Rap guanine nucleotide exchange factor (GEF) 6
Omim ID
610499Gene Ontology
HyperlinkOther Designations
PDZ domain containing guanine nucleotide exchange factor (GEF) 2|PDZ domain-containing guanine nucleotide exchange factor I
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Interactome
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Disease
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Publication Reference
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Critical function of RA-GEF-2/Rapgef6, a guanine nucleotide exchange factor for Rap1, in mouse spermatogenesis.
Okada K, Miyake H, Yamaguchi K, Chiba K, Maeta K, Bilasy SE, Edamatsu H, Kataoka T, Fujisawa M.
Biochemical and Biophysical Research Communications 2014 Feb; 445(1):89.
Application:IHC-P, Mouse, Testis.
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Critical function of RA-GEF-2/Rapgef6, a guanine nucleotide exchange factor for Rap1, in mouse spermatogenesis.
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