UPB1 monoclonal antibody (M09), clone 3F12
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More Files
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Western Blot (Tissue lysate)
UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in human liver.
Western Blot (Cell lysate)
UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in Jurkat ( Cat # L017V1 ).
Western Blot (Transfected lysate)
Western Blot analysis of UPB1 expression in transfected 293T cell line by UPB1 monoclonal antibody (M09), clone 3F12.
Lane 1: UPB1 transfected lysate (Predicted MW: 43.2 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to UPB1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UPB1 is 1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant UPB1.
Immunogen
UPB1 (NP_057411.1, 285 a.a. ~ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in human liver.Western Blot (Cell lysate)
UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in Jurkat ( Cat # L017V1 ).Western Blot (Transfected lysate)
Western Blot analysis of UPB1 expression in transfected 293T cell line by UPB1 monoclonal antibody (M09), clone 3F12.
Lane 1: UPB1 transfected lysate (Predicted MW: 43.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to UPB1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UPB1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — UPB1
Entrez GeneID
51733GeneBank Accession#
NM_016327Protein Accession#
NP_057411.1Gene Name
UPB1
Gene Alias
BUP1
Gene Description
ureidopropionase, beta
Omim ID
606673Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq
Other Designations
beta-alanine synthase|beta-ureidopropionase|n-carbamoyl-beta-alanine amidohydrolase
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Interactome
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Pathway
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Disease
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