OAZ3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human OAZ3 full-length ORF ( AAH73949.1, 1 a.a. - 190 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTVPWRPGKRRITYKEEEDLTLQPRPASSAPESLVGLQEGKSTEQGNHDQLKELYSAGNLTVLATDPLLHQDPVQLDFHFRLTSQTSAHWHGLLCDRRLFLDIPYQALDQGNRESLTATLEYVEEKTNVDSVFVNFQNDRNDRGALLRAFSYMGFEVVRPDHPALPPLDNVIFMVYPLERDVGHLPSEPP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
48.1
Interspecies Antigen Sequence
Mouse (81); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — OAZ3
Entrez GeneID
51686GeneBank Accession#
BC073949.1Protein Accession#
AAH73949.1Gene Name
OAZ3
Gene Alias
AZ3, OAZ-t, TISP15
Gene Description
ornithine decarboxylase antizyme 3
Omim ID
605138Gene Ontology
HyperlinkGene Summary
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
antizyme 3
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Interactome
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Disease
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