Transient overexpression cell lysate was tested with Anti-SUFU antibody (H00051684-D01P) by Western Blots. SDS-PAGE Gel SUFU transfected lysate. Western Blot Lane 1: SUFU transfected lysate ( 53.90 KDa) Lane 2: Non-transfected lysate.
Storage Buffer:
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).[supplied by OMIM
Other Designations:
OTTHUMP00000020374,OTTHUMP00000059161,suppressor of fused