SUFU (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SUFU partial ORF ( AAH13291, 181 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLSR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SUFU
Entrez GeneID
51684GeneBank Accession#
BC013291Protein Accession#
AAH13291Gene Name
SUFU
Gene Alias
PRO1280, SUFUH, SUFUXL
Gene Description
suppressor of fused homolog (Drosophila)
Gene Ontology
HyperlinkGene Summary
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).[supplied by OMIM
Other Designations
OTTHUMP00000020374|OTTHUMP00000059161|suppressor of fused
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Interactome
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Pathway
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