VPS24 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human VPS24 full-length ORF ( NP_057163.1, 1 a.a. - 222 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.5
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — VPS24
Entrez GeneID
51652GeneBank Accession#
NM_016079.2Protein Accession#
NP_057163.1Gene Name
VPS24
Gene Alias
CGI-149, CHMP3, NEDF
Gene Description
vacuolar protein sorting 24 homolog (S. cerevisiae)
Omim ID
610052Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
neuroendocrine differentiation factor|vacuolar protein sorting 24
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Interactome
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Pathway
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