MRPL48 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (49.43 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant MRPL48.
Immunogen
MRPL48 (AAH09764, 1 a.a. ~ 212 a.a) full-length recombinant protein with GST tag.
Sequence
MSGTLGKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEPKKKKGKVEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTIEVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHTEEDFKGRFKARPELEELLAKLK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (49.43 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MRPL48
Entrez GeneID
51642GeneBank Accession#
BC009764Protein Accession#
AAH09764Gene Name
MRPL48
Gene Alias
CGI-118, FLJ17047, FLJ99260, HSPC290, L48MT, MGC13323, MRP-L48
Gene Description
mitochondrial ribosomal protein L48
Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. [provided by RefSeq
Other Designations
39S ribosomal protein L48, mitochondrial
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Interactome
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Publication Reference
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Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome.
Metodiev MD, Lesko N, Park CB, Camara Y, Shi Y, Wibom R, Hultenby K, Gustafsson CM, Larsson NG.
Cell Metabolism 2009 Apr; 9(4):386.
Application：WB-Ti, Mouse, Mouse hearts.
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Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome.
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