SF3B14 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SF3B14 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SF3B14
Entrez GeneID
51639GeneBank Accession#
BC015463Protein Accession#
AAH15463Gene Name
SF3B14
Gene Alias
CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Gene Description
splicing factor 3B, 14 kDa subunit
Omim ID
607835Gene Ontology
HyperlinkGene Summary
This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. [provided by RefSeq
Other Designations
pre-mRNA branch site protein p14|spliceosome-associated protein, 14 kDa subunit
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Interactome
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Disease
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