SF3B14 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human SF3B14 full-length ORF ( ADZ15691.1, 1 a.a. - 125 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
13.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SF3B14
Entrez GeneID
51639GeneBank Accession#
JF432474.1Protein Accession#
ADZ15691.1Gene Name
SF3B14
Gene Alias
CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Gene Description
splicing factor 3B, 14 kDa subunit
Omim ID
607835Gene Ontology
HyperlinkGene Summary
This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. [provided by RefSeq
Other Designations
pre-mRNA branch site protein p14|spliceosome-associated protein, 14 kDa subunit
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Interactome
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Disease
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