AZIN1 monoclonal antibody (M02), clone 1F11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant AZIN1.
Immunogen
AZIN1 (NP_056962, 339 a.a. ~ 447 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HKKYKEDEPLFTSSLWGPSCDELDQIVESCLLPELNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQEDSFSAE
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — AZIN1
Entrez GeneID
51582GeneBank Accession#
NM_015878Protein Accession#
NP_056962Gene Name
AZIN1
Gene Alias
MGC3832, MGC691, OAZI, OAZIN, ODC1L
Gene Description
antizyme inhibitor 1
Omim ID
607909Gene Ontology
HyperlinkGene Summary
Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
ornithine decarboxylase 1-like|ornithine decarboxylase antizyme inhibitor
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