TTRAP monoclonal antibody (M01), clone 3D11
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TTRAP.
Immunogen
TTRAP (AAH17553, 1 a.a. ~ 362 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQLKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDIIL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (68)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (65.56 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to TTRAP on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TTRAP is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — TTRAP
Entrez GeneID
51567GeneBank Accession#
BC017553Protein Accession#
AAH17553Gene Name
TTRAP
Gene Alias
AD022, EAP2, MGC111021, MGC9099, dJ30M3.3
Gene Description
TRAF and TNF receptor associated protein
Omim ID
605764Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq
Other Designations
ETS1-associated protein 2|OTTHUMP00000016091|OTTHUMP00000039397|TRAF and TNF receptor-associated protein
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Interactome
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Disease
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